Sr. Scientist, Pharmacokinetics


Job title: Sr. Scientist, Pharmacokinetics

Firm: Merck & Co.

Job description: Job Description

R3 Sr. Scientist

Place title: Senior Scientist (R3), Discovery Bioanalytics

Place location: our Analysis & Improvement Division Boston, MA

The Division of Preclinical Improvement (PCD) is searching for a extremely gifted and motivated particular person to hitch our Discovery Bioanalytics group situated in Boston, MA. The profitable candidate will present enter into the design of experiments to develop and optimize strategies, consider new methods, trouble-shoot assays, and take a look at pre-clinical samples as wanted. The tasks of the Scientist might be to work collaboratively in a fast-paced surroundings to contribute to the help of drug discovery and pre-clinical research.

Fundamental Duties embrace however usually are not restricted to:

Designing, planning and executing new assays for the quantitative evaluation of exogenous and endogenous compounds (biotherapeutics, peptide, small molecule, oligonucleotides, biomarkers, and so on.) in samples from pharmacokinetic (PK), pharmacodynamics (PD), and endogenous metabolomic research from quite a lot of preclinical fashions and difficult matrices e.g. plasma, serum, cerebrospinal fluids, interstitial fluid and tissue homogenates.

Delivering prime quality quantitative information to challenge groups for PK, PK/PD and goal engagement research in help of our firm’s pipeline; making ready, reporting, and presenting scientific materials at inside cross-functional conferences.

Contributing to establishing and sustaining bioanalytical laboratory operations compliant with the State, Meso Scale Discovery and departmental security tips, trainings, and different relevant commonplace working procedures.

Training Minimal Necessities:

Ph.D. in Biology, Immunology, Molecular Biology, Chemistry, Biochemistry, Pharmaceutical Sciences, or associated self-discipline.

Grasp’s Diploma within the above talked about disciplines with 4+ years of related expertise.

B.A./B.S. Diploma within the above talked about disciplines with 6+ years of related expertise.

Required Expertise and Expertise:

Data concerning the event, validation, and troubleshooting of ligand binding assays together with bioanalysis of huge molecules by ELISA, Meso Scale Discovery, and different platforms.

A crew participant with wonderful oral and written communication abilities as evidenced by scientific publications and shows at scientific conferences.

Familiarity with the fundamental ideas of regulated bioanalysis and Good Laboratory Apply.

Expertise supporting the bioanalysis of various biotherapeutic modalities.

Potential to work independently below average supervision and work nicely in groups – dedicated to working synergistically and harmoniously with others.

Most well-liked Expertise and Expertise:

Expertise within the discipline of bioanalysis through ligand binding strategies or LC-MS to help the PK and PD elements of drug discovery research is very most popular.

Robust hands-on expertise with ligand-binding and molecular assays akin to ELISA, hybridization ELISA, Gyros, qPCR, and so on. OR with chromatographic separation and mass spectrometry methodologies (LC/MS) to help quantitative evaluation of biotherapeutics or small molecules.

Expertise in executing routine bioanalytical assays, and information processing utilizing Softmax Professional, Watson, and so on.

Good analytical and problem-solving abilities; Should be deadline pushed and have a excessive degree of organizational and planning functionality.

Good verbal & written communication abilities and current concepts clearly and concisely. Profitable candidate offers first-authored, inside and exterior experiences and shows on technical and scientific findings.

We’re a research-driven biopharmaceutical firm. Our mission is constructed on the easy premise that if we “comply with the science” that nice medicines could make a major impression to our world. We consider {that a} research-driven enterprise devoted to world-class science can succeed by inventing medication and vaccine improvements that make a distinction for sufferers throughout the globe.

Who we’re …

We’re often known as Merck & Co., Inc., Rahway, New Jersey, USA in the US and Canada and MSD in every single place else. For greater than a century, we have now been inventing for all times, bringing ahead medicines and vaccines for lots of the world’s most difficult ailments. Right this moment, our firm continues to be on the forefront of analysis to ship modern well being options and advance the prevention and therapy of ailments that threaten folks and animals around the globe.

What we search for …

Think about getting up within the morning for a job as essential as serving to to avoid wasting and enhance lives around the globe. Right here, you’ve that chance. You possibly can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a various group of colleagues who pursue and convey hope to numerous people who find themselves battling a few of the most difficult ailments of our time. Our crew is consistently evolving, so in case you are among the many intellectually curious, be a part of us—and begin making your impression right this moment.


In accordance with all workers topic to this coverage are required to have a minimal of twelve (12) months of service in present place previous to making use of for open positions.

When you have been provided a separation advantages bundle, however haven’t but reached your separation date and are provided a place inside the wage and geographical parameters as set forth within the Abstract Plan Description (SPD) of your separation bundle, then you’re not eligible in your separation advantages bundle. To debate in additional element, please contact your HRBP or Expertise Acquisition Advisor.

New hires in office-based roles within the US & Puerto Rico might be required, topic to relevant legislation, to display that they’ve been absolutely vaccinated for COVID-19 or qualify for a medical or non secular exemption to this vaccination requirement that may be accommodated with out an undue burden to the operation. Nonetheless, topic to relevant legislation, workers working in roles that the Firm determines require routine collaboration with exterior stakeholders, akin to workers in well being companies, buyer dealing with industrial, or analysis based mostly roles, might be required to be absolutely vaccinated as a situation of employment.

Present Staff apply

Present Contingent Employees apply

US and Puerto Rico Residents Solely:

Our firm is dedicated to inclusion, making certain that candidates can interact in a hiring course of that reveals their true capabilities. Please when you want an lodging in the course of the software or hiring course of.

For extra details about private rights below Equal Employment Alternative, go to:

We’re proud to be an organization that embraces the worth of bringing numerous, gifted, and dedicated folks collectively. The quickest technique to breakthrough innovation is when numerous concepts come collectively in an inclusive surroundings. We encourage our colleagues to respectfully problem each other’s pondering and method issues collectively. We’re an equal alternative employer, dedicated to fostering an inclusive and numerous office.

Search Agency Representatives Please Learn Rigorously
Merck & Co., Inc., Rahway, NJ, USA, often known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, doesn’t settle for unsolicited help from search companies for employment alternatives. All CVs / resumes submitted by search companies to any worker at our firm and not using a legitimate written search settlement in place for this place might be deemed the only real property of our firm. No price might be paid within the occasion a candidate is employed by our firm on account of an company referral the place no pre-existing settlement is in place. The place company agreements are in place, introductions are place particular. Please, no cellphone calls or emails.

Worker Standing: Common

Relocation: Home

VISA Sponsorship: Sure

Journey Necessities: No Journey Required

Versatile Work Preparations:


Legitimate Driving License: Sure

Hazardous Materials(s):

Variety of Openings: 1

Anticipated wage:

Location: Boston, MA

Job date: Mon, 11 Jul 2022 07:15:15 GMT

Apply for the job now!

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